Trimethoprim-Sulphamethoxazole Or Doxycycline Outcomesfor Skin Infections
What is the purpose of the study?
The purpose of this study is to compare how well two different antibiotics work at curing skin infections. The antibiotics used in this study have been commonly used by doctors to treat certain types of infections for many years. However, even though these antibiotics are used often, it is not known if one of the drugs is better than the
other at treating skin infections. The study will also see if one of the antibiotics is safer than the other.
The antibiotics that will be used in this study are doxycycline (DOXY) and trimethoprim/sulfamethoxazole (TMP/SMX). Both antibiotics are approved by the United States Food and Drug Administration (FDA) to treat different types of infections. The FDA has not approved these two antibiotics for the treatment of skin infections.
However, both antibiotics are commonly recommended (and used off label which is allowed by the FDA) by experts to treat skin infections.
If you take part in this study, you agree to:
Come to the study clinic for the planned visits.
Able to take oral antibiotic therapy, either in pill or suspension form
Complete a medication diary in which you will record the time you take your study medication and any other medicine you take each day.
You will also need to record any side effects you may be experiencing and how you are feeling each day. It should take at most about 5 minutes to complete the diary each day for the 7 days you are taking the study medication.
• You will need to bring this diary with you to your next study visit.
• Follow the study doctor’s and study staff’s instructions.
© 2023 ID CORE at The Lundquist Institute For Biomedical Innovation at Harbor-UCLA Medical Center